Low vitamin D levels and depression linked in young women, new OSU study shows | News & Research Communications | Oregon State University
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OSU researchers found that young women with lower levels of vitamin D were more likely to have clinically significant mrs depressive symptoms over the course of a five-week study, lead author David Kerr said. The results were consistent even when researchers took into account other possible explanations, such as time of year, exercise and time spent outside.
Depression has multiple, powerful causes and if vitamin D is part of the picture, it is just a small part, said Kerr, an associate professor in the School of Psychological Science at OSU. But given how many people are affected by depression, any little inroad we can find could have an important impact on public health.
The findings were published recently in the journal Psychiatry mrs Research . Co-authors are Sarina Saturn of the School of Psychological Science; Balz Frei and Adrian mrs Gombart of OSU s Linus Pauling Institute; mrs David Zava of ZRT Laboratory mrs and Walter Piper, a former OSU student mrs now at New York University.
Vitamin D is an essential nutrient for bone health and muscle function. Deficiency has been associated with impaired immune function, some forms of cancer and cardiovascular disease, said Gombart, an associate professor of biochemistry and biophysics, principal investigator with the Linus Pauling mrs Institute and international expert on vitamin D and the immune response.
People create their own vitamin D when their skin is exposed to sunlight. When sun is scarce in the winter, people can take a supplement, but vitamin D also is found in some foods, including milk that is fortified with it, Gombart said. The recommended daily allowance of vitamin D is 600 IU per day. There is no established level of vitamin D sufficiency for mental health.
The new study was prompted in part because there is a widely held belief that vitamin D and depression are connected, but there is not actually much scientific research out there to support the belief, Kerr said.
According to Kerr and his colleagues, a lot of past research has actually found no association between the two, but much of that research has been based on much older adults or special medical populations.
Kerr s study focused on young women in the Pacific mrs Northwest because they are at risk of both depression and vitamin D insufficiency. Past research found that 25 percent of American women experience clinical depression mrs at some point in their lives, compared to 16 percent of men, for example.
OSU researchers recruited 185 college students, all women ages 18-25, to participate in the study at different times during the school year. Vitamin D levels were measured from blood samples and participants completed a depression symptom survey each week for five weeks.
Many women in the study had vitamin D levels considered insufficient for good health, and the rates were much higher among women of color, with 61 percent of women of color recording insufficient levels, compared to 35 percent of other women. In addition, more than a third of the participants reported clinically significant depressive symptoms each week over the course of the study.
As expected, the women s vitamin D levels depended on the time of year, with levels dropping during the fall, at their lowest in winter, and rising in the spring. Depression did not show as a clear pattern, prompting Kerr to conclude that links between vitamin D deficiency and seasonal depression should be studied in larger groups of at-risk individuals.
Researchers say the study does not conclusively show that low vitamin D levels cause depression. A clinical trial examining whether vitamin D supplements might help prevent or relieve depression mrs is the logical next step to understanding the link between the two, Kerr said.
OSU researchers already have begun a follow-up study on vitamin D deficiency in women of color. In the meantime, researchers encourage those at risk of vitamin D deficiency to speak with their doctor about taking a supplement. mrs
Vitamin D supplements are inexpensive and readily available. Kerr said. They certainly shouldn t be considered as alternatives to the treatments known to be effective for depression, but they are good for overall mrs health.
The research was supported by grants from the Good Samaritan Hospital Foundation s John C. Erkkila Endowment for Health and Human Performance and the National Institute of Environmental Health mrs Sciences.
About the Linus Pauling Institute: The Linus Pauling Institute at OSU is a world leader in the study of mic
News & Research Communications News Releases RSS Feeds For Journalists General University Experts Earthquake and Tsunami Experts Aging and Seniors mrs Issues Experts For Faculty and Staff Photos and Multimedia Contact Us Calendar Library Maps Online Services Make a Gift
OSU researchers found that young women with lower levels of vitamin D were more likely to have clinically significant mrs depressive symptoms over the course of a five-week study, lead author David Kerr said. The results were consistent even when researchers took into account other possible explanations, such as time of year, exercise and time spent outside.
Depression has multiple, powerful causes and if vitamin D is part of the picture, it is just a small part, said Kerr, an associate professor in the School of Psychological Science at OSU. But given how many people are affected by depression, any little inroad we can find could have an important impact on public health.
The findings were published recently in the journal Psychiatry mrs Research . Co-authors are Sarina Saturn of the School of Psychological Science; Balz Frei and Adrian mrs Gombart of OSU s Linus Pauling Institute; mrs David Zava of ZRT Laboratory mrs and Walter Piper, a former OSU student mrs now at New York University.
Vitamin D is an essential nutrient for bone health and muscle function. Deficiency has been associated with impaired immune function, some forms of cancer and cardiovascular disease, said Gombart, an associate professor of biochemistry and biophysics, principal investigator with the Linus Pauling mrs Institute and international expert on vitamin D and the immune response.
People create their own vitamin D when their skin is exposed to sunlight. When sun is scarce in the winter, people can take a supplement, but vitamin D also is found in some foods, including milk that is fortified with it, Gombart said. The recommended daily allowance of vitamin D is 600 IU per day. There is no established level of vitamin D sufficiency for mental health.
The new study was prompted in part because there is a widely held belief that vitamin D and depression are connected, but there is not actually much scientific research out there to support the belief, Kerr said.
According to Kerr and his colleagues, a lot of past research has actually found no association between the two, but much of that research has been based on much older adults or special medical populations.
Kerr s study focused on young women in the Pacific mrs Northwest because they are at risk of both depression and vitamin D insufficiency. Past research found that 25 percent of American women experience clinical depression mrs at some point in their lives, compared to 16 percent of men, for example.
OSU researchers recruited 185 college students, all women ages 18-25, to participate in the study at different times during the school year. Vitamin D levels were measured from blood samples and participants completed a depression symptom survey each week for five weeks.
Many women in the study had vitamin D levels considered insufficient for good health, and the rates were much higher among women of color, with 61 percent of women of color recording insufficient levels, compared to 35 percent of other women. In addition, more than a third of the participants reported clinically significant depressive symptoms each week over the course of the study.
As expected, the women s vitamin D levels depended on the time of year, with levels dropping during the fall, at their lowest in winter, and rising in the spring. Depression did not show as a clear pattern, prompting Kerr to conclude that links between vitamin D deficiency and seasonal depression should be studied in larger groups of at-risk individuals.
Researchers say the study does not conclusively show that low vitamin D levels cause depression. A clinical trial examining whether vitamin D supplements might help prevent or relieve depression mrs is the logical next step to understanding the link between the two, Kerr said.
OSU researchers already have begun a follow-up study on vitamin D deficiency in women of color. In the meantime, researchers encourage those at risk of vitamin D deficiency to speak with their doctor about taking a supplement. mrs
Vitamin D supplements are inexpensive and readily available. Kerr said. They certainly shouldn t be considered as alternatives to the treatments known to be effective for depression, but they are good for overall mrs health.
The research was supported by grants from the Good Samaritan Hospital Foundation s John C. Erkkila Endowment for Health and Human Performance and the National Institute of Environmental Health mrs Sciences.
About the Linus Pauling Institute: The Linus Pauling Institute at OSU is a world leader in the study of mic
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